Abstract:

The study of new  intervention methods on dry eye mainly focuses on maintaining the balance of ocular surface microenvironment, primarily including the following three aspects. (1)Anti-inflammation such as reducing the expression of inflammation factors and damage-associated molecular patterns(DAMPs). (2)Anti-oxidation such as maintaining the balance between oxidase and antioxidant enzymes and activing endoplasmic reticulum stress. (3)Maintaining stability of tear film by increasing the content of mucin and lipid.(Int Rev Ophthalmol,  2017,  41:   400-405)